Prior to moving to New York, Ana lived in San Francisco, California, where she performed at the drag club Trannyshack and reached the finals of the Miss Trannyshack pageant. It was her experience at Trannyshack that inspired her to start the club Knockoff on the Lower East Side of Manhattan, intended as a "knockoff" version of Trannyshack. She joined Scissor Sisters, founded by Jake Shears and Babydaddy, after they played their first live gig at the club.
She has stated that in her eyes, the objective of the band is "about people displaying their fantasies on the outside, trying to break out of the everyday, and look like their dreams." In the fan community for the Scissor Sisters, those fans who hold a special affinity for Ana are known as "nuns". A unique following of both heterosexual men and homosexual women who are attracted to Ana term themselves "Anasexual".
In 2004, she revealed to British magazine that her parents' marriage broke up when she was a toddler due to her father's homosexuality, and that her father died of an AIDS related illness when she was 15. She also stated in this interview that her immersion in gay culture is probably an attempt to feel closer to him, and understand who her father was as a person.
To me Ana embraces beauty who's happy within her own skin, talented and fierce. Everything little girls dream of really........and big girls!